Yes — our Biome Balance Renew Night Cream and other PhycoHealth skincare can be used safely with retinal (retinaldehyde) or retinol products. In fact, they often make the perfect partners.

Here’s why:

  • Renew is designed to restore balance and hydration while supporting the skin’s natural microbiome.

  • It contains our Phyaluronic® seaweed extract, niacinamide, Centella, and Bakuchiol® — ingredients known to calm, strengthen, and replenish the skin barrier.

  • These soothing and antioxidant properties help to reduce the dryness or sensitivity that can sometimes occur with retinal or retinol use.

How to layer them:

  1. Apply your retinal or retinol serum first, on clean, dry skin.

  2. Wait about 5–10 minutes for absorption.

  3. Follow with Renew Night Cream to lock in moisture and support overnight repair.

  4. If your skin is new to vitamin A, alternate nights or mix a small amount of both in your palm for a gentler start.

Good to know:

  • Bakuchiol®, found in our Renew Night Cream, is not a vitamin A compound but a functionally retinol-like, plant-based molecule that complements retinal without duplication.

  • Together, they provide renewal with balance — collagen support, smoother texture, and healthy barrier function without the irritation.